Lebeau G, Hoareau M, Rivière S, El Safadi D, Da Silva CR, Krejbich-Trotot P, Viranaicken W.  Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome ? Biochimie. 2024 Feb 1;221:75-80.

Atchade E, De Tymowski C, Grall N, Tanaka S, Montravers P.
Toxic Shock Syndrome: A Literature Review. Antibiotics (Basel). 2024 Jan 18;13(1):96.


El Safadi D, Lebeau G, Turpin J, Lefebvre d’Hellencourt C, Diotel N, Viranaicken W, Krejbich-Trotot P.  The Antiviral Potential of AdipoRon, an Adiponectin Receptor Agonist, Reveals the Ability of Zika Virus to Deregulate Adiponectin Receptor Expression. Viruses. 2023 Dec 22;16(1):24.

El Safadi D, Paulo-Ramos A, Hoareau M, Roche M, Krejbich-Trotot P, Viranaicken W, Lebeau G.  The Influence of Metabolism on Immune Response: A Journey to Understand Immunometabolism in the Context of Viral Infection. Viruses. 2023 Dec 9;15(12):2399.

Begue F, Apalama ML, Lambert G, Meilhac O. HDL as a Treatment Target: Should We Abandon This Idea ? Curr Atheroscler Rep. 2023 Dec;25(12):1093-1099.

Turpin T, Thouvenot K, Gonthier MP. Adipokines and Bacterial Metabolites: A Pivotal Molecular Bridge Linking Obesity and Gut Microbiota Dysbiosis to Target. Biomolecules. 2023 Nov 23;13(12):1692.

Lebeau G, El Safadi D, Hoarau M, Meilhac O, Krejbich-Trotot P, Viranaicken W.
Zika virus restriction of host antioxidant response is mediated by intracellular NS1 and reveals its ability to upregulate Bach1 expression. Biochem Biophys Res Commun. 2023 Nov 23;690:149312.

Pellegrini E, Fernezelian D, Malleret C, Gueguen MM, Patche-Firmin J, Rastegar S, Meilhac O, Diotel N.  Estrogenic regulation of claudin 5 and tight junction protein 1 gene expression in zebrafish: A role on blood-brain barrier? J Comp Neurol. 2023 Dec;531(17):1828-1845.

Gence L, Fernezelian D, Meilhac O, Rastegar S, Bascands JL, Diotel N. Insulin signaling promotes neurogenesis in the brain of adult zebrafish. J Comp Neurol. 2023 Dec;531(17):1812-1827.

Pellegrini E, Fernezelian D, Malleret C, Gueguen MM, Patche-Firmin J, Rastegar S, Meilhac O, Diotel N. Estrogenic regulation of claudin 5 and tight junction protein 1 gene expression in zebrafish: A role on blood-brain barrier? J Comp Neurol. 2023 Dec;531(17):1828-1845.

Caillaud A, Bray L, Girardeau A, Begué-Racapé Z, Vince L, Patitucci M, Le May C, Lambert G, Cariou B, Rimbert A. Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels. Stem Cell Res. 2023 Sep 15;72:103205.

Sonneville R, Mazighi M, Collet M, Gayat E, Degos V, Duranteau J, Grégoire C, Sharshar T, Naim G, Cortier D, Jost PH, Foucrier A, Bagate F, de Montmollin E, Papin G, Magalhaes E, Guidet B, Ben Hadj Salem O, Benghanem S, le Guennec L, Delpierre E, Legriel S, Megarbane B, Toumert K, Tran M, Geri G, Monchi M, Bodiguel E, Mariotte E, Demoule A, Zarka J, Diehl JL, Roux D, Barré E, Tanaka S, Osman D, Pasquier P, Lamara F, Crassard I, Boursin P, Ruckly S, Staiquly Q, Timsit JF, Woimant F; SPICE Investigators.  One-Year Outcomes in Patients With Acute Stroke Requiring Mechanical Ventilation. Stroke. 2023 Sep;54(9):2328-2337.

Narra SS, Gence L, Youssouf L, Couprie J, Giraud P, Diotel N, Lefebvre D’Hellencourt C. Curcumin-Encapsulated Nanomicelles Promote Tissue Regeneration in Zebrafish Eleutheroembryo. Zebrafish. 2023 Aug 29. doi: 10.1089/zeb.2023.0007.

Castillo S, Gence R, Pagan D, Koraïchi F, Bouchenot C, Pons BJ, Boëlle B, Olichon A, Lajoie-Mazenc I, Favre G, Pédelacq JD, Cabantous S. Visualizing the subcellular localization of RHOB-GTP and GTPase-Effector complexes using a split-GFP/nanobody labelling assay. Eur J Cell Biol. 2023 Aug 21;102(4):151355.

Jaafar AK, Techer R, Chemello K, Lambert G, Bourane S. PCSK9 and the nervous system: a no-brainer ?. J Lipid Res. 2023 Aug 14;64(9):100426.

Chiappetta S, de Falco N, Lainas P, Kassir R, Valizadeh R, Kermansaravi M. Safety and efficacy of Roux-en-Y gastric bypass as revisional bariatric surgery after failed anti-reflux surgery: a systematic review. Surg Obes Relat Dis. 2023 Jun 8:S1550-7289(23)00567-1.

Azúa-López ZR, Pezzotti MR, González-Díaz Á, Meilhac O, Ureña J, Amaya-Villar R, Castellano A, Varela LM. HDL anti-inflammatory function is impaired and associated with high SAA1 and low APOA4 levels in aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2023 Jun 26:271678X231184806.

Guérin M, Remize F, Bringart M, Planesse C, Rondeau P, Da Silva CR, Garcia C. Fermented pineapple juice consumption limits metabolic disorders associated to sugary drinks on high-fat diet-fed mice. Mol Nutr Food Res. 2023 Jun;67(11):e2200670.

Atchade E, Boughaba A, Dinh AT, Jean-Baptiste S, Tanaka S, Copelovici L, Lortat-Jacob B, Roussel A, Castier Y, Messika J, Mal H, de Tymowski C, Montravers P. Prolonged mechanical ventilation after lung transplantation: risks factors and consequences on recipient outcome. Front Med (Lausanne). 2023 May 9;10:1160621.

Kermansaravi M, Kassir R, Valizadeh R, Parmar C, Davarpanah AH, Shahmiri SS, Benois M. Management of leaks following one anastomosis gastric by pass: An updated systematic review and meta-analysis of 44318 patients. Int J Surg 2023 May 1;109(5):1497-1508.

Kronenberg F, Mora S, Stroes ESG, Ference BA, Arsenault BJ, Berglund L, Dweck MR, Koschinsky ML, Lambert G, Mach F, McNeal CJ, Moriarty PM, Natarajan P, Nordestgaard BG, Parhofer KG, Virani SS, von Eckardstein A, Watts GF, Stock JK, Ray KK, Tokgözoğlu LS, Catapano AL. Atherosclerosis. 2023 Apr 28:S0021-9150(23)00182-X.

Treiber G, Gonthier MP, Guilleux A, Medjane S, Bonfanti O, Cogne M, Meilhac O, Nobecourt E. Familial partial lipodystrophy type 2 and obesity, two adipose tissue pathologies with different inflammatory profiles. Diabetol Metab Syndr. 2023 Apr 21;15(1):77.

Atchade E, Arsène A, Jean-Baptiste S, Tran Dinh A, Tanaka S, Stern J, Lortat-Jacob B, Rosencwajg S, Goletto T, Mal H, Ben Adballah I, Castier Y, de Tymowski C, Montravers P. Donors brain-dead after successful resuscitation of cardiac arrest: Early outcome and postoperative complications of lung recipients. Resuscitation. 2023 Mar;184:109720.

Treiber G, Guilleux A, Huynh K, Bonfanti O, Flaus-Furmaniuk A, Couret D, Mellet N, Bernard C, Le-Moullec N, Doray B, Jéru I, Maiza JC, Domun B, Cogne M, Meilhac O, Vigouroux C, Meikle PJ, Nobécourt E. Lipoatrophic diabetes in Familial Partial Lipodystrophy type 2: from insulin resistance to diabetes. Diabetes Metab. 2023 Mar;49(2):101409.

Dorsemans AC, Essop MF, Bourdon E. Can the introduction of an authentic learning exercise lead to the modulation of breakfast behavior in undergraduate students at University of La Réunion ? Adv Physiol Educ. 2023 Mar 1;47(1):93-96.

Begue F, Chemello K, Veeren B, Lortat-Jacob B, Tran-Dinh A, Zappella N, Snauwaert A, Robert T, Rondeau P, Lagrange-Xelot M, Montravers P, Couret D, Tanaka S, Meilhac O. Plasma Apolipoprotein Concentrations Are Highly Altered in Severe Intensive Care Unit COVID-19 Patients: Preliminary Results from the LIPICOR Cohort Study. Int J Mol Sci. 2023 Feb 27;24(5):4605.

Narra SS, Rondeau P, Fernezelian D, Gence L, Ghaddar B, Bourdon E, Lefebvre d’Hellencourt C, Rastegar S, Diotel N. Distribution of microglia/immune cells in the brain of adult zebrafish in homeostatic and regenerative conditions: Focus on oxidative stress during brain repair. J Comp Neurol. 2023 Feb;531(2):238-255.

Tran-Dinh A, Tir I, Tanaka S, Atchade E, Lortat-Jacob B, Jean-Baptiste S, Zappella N, Boudinet S, Castier Y, Mal H, Mordant P, Ben Abdallah I, Bunel V, Messika J, Armand-Lefèvre L, Grall N, Montravers P. Impact of Culture-Positive Preservation Fluid on Early Morbidity and Mortality After Lung Transplantation. Transpl Int. 2023 Feb 8;36:10826.

Hofmaenner DA, Arina P, Kleyman A, Page Black L, Salomao R, Tanaka S, Guirgis FW, Arulkumaran N, Singer M. Association Between Hypocholesterolemia and Mortality in Critically Ill Patients With Sepsis: A Systematic Review and Meta-Analysis. Crit Care Explor. 2023 Feb 1;5(2):e0860.

Tanaka S, Montravers P. Therapeutic implications of the microbiology of severe skin infections. Rev Prat. 2023 Feb;73(2):160-164.

Safadi DE, Lebeau G, Lagrave A, Mélade J, Grondin L, Rosanaly S, Begue F, Hoareau M, Veeren B, Roche M, Hoarau JJ, Meilhac O, Mavingui P, Desprès P, Viranaïcken W, Krejbich-Trotot P. Extracellular Vesicles Are Conveyors of the NS1 Toxin during Dengue Virus and Zika Virus Infection. Viruses. 2023 Jan 27;15(2):364.

Tanaka S, Tymowski C, Tran-Dinh A, Meilhac O, Lortat-Jacob B, Zappella N, Jean-Baptiste S, Robert T, Goletto T, Godet C, Castier Y, Mal H, Mordant P, Atchade E, Messika J, Montravers P; Bichat Lung Transplant Group. Low HDL-Cholesterol Concentrations in Lung Transplant Candidates are Strongly Associated With One-Year Mortality After Lung Transplantation. Transpl Int. 2023 Jan 16;36:10841.

Mhalhel K, Sicari M, Pansera L, Chen J, Levanti M, Diotel N, Rastegar S, Germanà A, Montalbano G. Zebrafish: A Model Deciphering the Impact of Flavonoids on Neurodegenerative Disorders. Cells. 2023 Jan 7;12(2):252.

McPherson CA, Kelly-Rajan K, Lefebvre d’Hellencourt C, Harry GJ. High Content Imaging and Quantification of Microglia Phagocytosis In Vitro. Curr Protoc. 2023 Jan;3(1):e638.

Ramlagan P, Issa MY, Rondeau P, Bourdon E, Bahorun T, Farag MA, Neergheen VS. Metabolite Profiling of Antioxidant Rich Fractions of Punica granatum L. Mesocarp and CD36 Expression Regulation. J Am Nutr Assoc. 2023 Jan;42(1):36-54.




Atchade E, Ren M, Jean-Baptiste S, Tran Dinh A, Tanaka S, Tashk P, Lortat-Jacob B, Assadi M, Weisenburger G, Mal H, Sénémaud JN, Castier Y, de Tymowski C, Montravers P. ECMO support as a bridge to lung transplantation is an independent risk factor for bronchial anastomotic dehiscence. BMC Pulm Med. 2022 Dec 20;22(1):482.

Ramiharimanana FD, Haddad JG, Andrianavalonirina MA, Apel C, Olivon F, Diotel N, Desprès P, Ramanandraibe VV, El Kalamouni C. Antiviral Effect of Stenocline ericoides DC. and Stenocline inuloides DC., Two Flavonoid-Rich Endemic Plants from Madagascar, against Dengue and Zika Viruses. Pharmaceuticals (Basel). 2022 Nov 30;15(12):1500.

Anthony N, Bruneau L, Leruste S, Franco JM, Domercq A, Kowalczyk C, Nobecourt E, Marimoutou C. Diabetes incidence in subjects with PREDIABetes from ReUNion Island: the PREDIABRUN observational cohort study protocol. BMJ Open. 2022 Nov 21;12(11):e062520.

Turpin C, Meilhac O, Bourdon E, Canonne-Hergaux F, Rondeau P. Methodologies and tools to shed light on erythrophagocytosis. Biochimie. 2022  Nov;202:166-179.

Tran-Dinh A, Slassi L, De Tymowski C, Assadi M, Tanaka S, Zappella N, Lortat Jacob B, Jean-Baptiste S, Atchade E, Castier Y, Mal H, Mordant P, Armand-Lefèvre L, Messika J, Grall N, Montravers P. Secondary Prophylaxis With Inhaled Colistin to Prevent Recurrence of Pseudomonas aeruginosa and Extended-spectrum β-lactamase-producing Enterobacterales Pneumonia in ICU After Lung Transplantation: A Before-and-after Retrospective Cohort Analysis. Transplantation. 2022 Nov 1;106(11):2232-2240.

Suchowerska AK, Stokman G, Palmer JT, Coghlan PA, Pieterman EJ, Keijzer N, Lambert G, Chemello K, Jaafar AK, Parmar J, Yan L, Tong Y, Mu L, Princen HMG, Bonnar J, Evison BJ. J Lipid Res. 2022 Nov;63(11):100293.

Lebeau G, El Safadi D, Paulo-Ramos A, Hoareau M, Desprès P, Krejbich-Trotot P, Chouchou F, Roche M, Viranaicken W. The Efficient Antiviral Response of A549 Cells Is Enhanced When Mitochondrial Respiration Is Promoted. Pathogens. 2022 Oct 11;11(10):1168.

Tran-Dinh A, Guiot M, Tanaka S, Lortat-Jacob B, Atchade E, Zappella N, Mordant P, Castier Y, Mal H, Weisenburger G, Messika J, Grall N, Montravers P. Bacteraemia Is Associated with Increased ICU Mortality in the Postoperative Course of Lung Transplantation. Antibiotics (Basel). 2022 Oct 13;11(10):1405.

Zappella N, Dirani C, Lortat Jacob B, Tanaka S, Kantor E, El Kalai A, Rkik Y, Gouel Cheron A, Tran Dinh A, Montravers P. Temporary ICUs during the COVID-19 pandemic first wave: description of the cohort at a French centre. BMC Anesthesiol. 2022 Oct 3;22(1):310.

Atchade E, Elmaleh Y, Zappella N, Jean-Baptiste S, Tran-Dinh A, Tanaka S, Snauwaert A, Lortat-Jacob B, Goncalves O, Godet C, Mal H, CAstier Y, De Tymowski C, Montravers P. Massive intraoperative red blood cell transfusion during lung transplantation is strongly associated with 90-day mortality. Anaesth Crit Care Pain Med. 2022 Oct;41(5):101118.

Tran-Dinh A, Laurent Q, Even G, Tanaka S, Lortat-Jacob B, Castier Y, Mal H, Messika J, Mordant P, Nicoletti A, Montravers P, Caligiuri G, Morilla I. Personalized risk predictor for acute cellular rejection in lung transplant using soluble CD31. Sci Rep. 2022 Oct 21;12(1):17628.

Peretti N, Vimont A, Mas E, Ferrières J, Tounian P, Lemale J, Boccara F, Di Filippo M, Charriere S, P M, Poinsot P, Cottin Y, Ducluzeau PH, Dourmap C, Cariou B, Farnier M, Paillard F, Pradignac A, Yelnik C, Gallo A, Bruckert E, Beliard S; French REgistry of Familial hypERCHOLesterolemia (REFERCHOL) investigators. Factors predicting statin initiation during childhood in familial hypercholesterolemia: importance of genetic diagnosis. J Pediatr. 2022 Aug 29:S0022-3476(22)00777-6.

Kronenberg F, Mora S, Stroes ESG, Ference BA, Arsenault BJ, Berglund L, Dweck MR, Koschinsky M, Lambert G, Mach F, McNeal CJ, Moriarty PM, Natarajan P, Nordestgaard BG, Parhofer KG, Virani SS, von Eckardstein A, Watts GF, Stock JK, Ray KK, Tokgözoğlu LS, Catapano AL. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J. 2022 Aug 29:ehac361.

Tran-Dinh A, Bouzid D, El Kalai A, Atchade E, Tanaka S, Lortat-Jacob B, Jean-Baptiste S, Zappella N, Boudinet S, Castier Y, Mal H, Mordant P, Messika J, Montravers P. Favorable, arduous or fatal postoperative pathway within 90 days of lung transplantation. BMC Pulm Med. 2022 Aug 27;22(1):326.

Keller L, Tardy C, Ligat L, Le Pennec S, Bery N, Koraïchi F, Chinestra P, David M, Gence R, Favre G, Cabantous S, Olichon A. Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling. Front Immunol. 2022 Aug 18;13:980539.

Tanaka S, De Tymowski C, Stern J, Bouzid D, Zappella N, Snauwaert A, Robert T, Lortat-Jacob B, Tran-Dinh A, Augustin P, Boutten A, Tashk P, Peoc’h K, Meilhac O, Montravers P. Relationship between liver dysfunction, lipoprotein concentration and mortality during sepsis. PLoS One. 2022 Aug 22;17(8):e0272352.

Turpin C, Apalama ML, Carnero B, Otero-Cacho A, Munuzuri AP, Flores-Arias MT, Vélia E, Meilhac O, Bourdon E, Álvarez E, Rondeau P. Impact of Enhanced Phagocytosis of Glycated Erythrocytes on Human Endothelial Cell Functions. Cells. 2022 Jul 14;11(14):2200.

Blanchard V, Chemello K, Hollstein T, Hong-Fong CC, Schumann F, Grenkowitz T, Nativel B, Coassin S, Croyal M, Kassner U, Lamina C, Steinhagen-Thiessen E, Lambert G. The size of apolipoprotein (a) is an independent determinant of the reduction in lipoprotein (a) induced by PCSK9 inhibitors. Cardiovasc Res. 2022 Jul 20;118(9):2103-2111.

Chiappetta S, Lainas P, Kassir R, Valizadeh R, Bosco A, Kermansaravi M. Gastroesophageal Reflux Disease as an Indication of Revisional Bariatric Surgery-Indication and Results-a Systematic Review and Metanalysis. Obes Surg. 2022 Jul 1.

Sow MA, Magne J, Salle L, Nobecourt E, Preux PM, Aboyans V. Prevalence, determinants and prognostic value of high coronary artery calcium score in asymptomatic patients with diabetes: A systematic review and meta-analysis. J Diabetes Complications. 2022 Jun 26:108237.

Ghaddar B, Gence L, Veeren B, Bringart M, Bascands JL, Meilhac O, Diotel N, Aqueous Extract of Psiloxylon mauritianum, Rich in Gallic Acid, Prevents Obesity and Associated Deleterious Effects in Zebrafish. Antioxidants (Basel). 2022 Jun 30;11(7):1309.

Lecoin L, Dempsey B, Garancher A, Bourane S, Ruffault PL, Morin-Surun MP, Rocques N, Goulding M, Eychène A, Pouponnot C, Fortin G, Champagnat J. Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nat Commun. 2022 Jun 7;13(1):3284. doi: 10.1038/s41467-022-30825-3.

Clain J, Couret D, Planesse C, Krejbich-Trotot P, Meilhac O, Lefebvre d’Hellencourt C, Viranaicken W, Diotel N.  Distribution of Adiponectin Receptors in the Brain of Adult Mouse: Effect of a Single Dose of the Adiponectin Receptor Agonist, AdipoRON, on Ischemic Stroke. Brain Sci. 2022 May 23;12(5):680.

Tamkutė L, Haddad JG, Diotel N, Desprès P, Venskutonis PR, El Kalamouni C. Cranberry Pomace Extract Exerts Antiviral Activity against Zika and Dengue Virus at Safe Doses for Adult Zebrafish. Viruses. 2022 May 20;14(5):1101.

Chemello K, Chan DC, Lambert G, Watts GF. Recent advances in demystifying the metabolism of lipoprotein(a). Atherosclerosis. 2022 May;349:82-91.

Ghaddar B, Diotel N. Zebrafish: A New Promise to Study the Impact of Metabolic Disorders on the Brain. Int J Mol Sci. 2022 May 11;23(10):5372.

Benito-Vicente A, Uribe KB, Larrea-Sebal A, Palacios L, Cenarro A, Calle X, Galicia-Garcia U, Jebari S, Sánchez-Hernández RM, Stef M, Lambert G, Civeira F, Martín C. Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant Hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2022 May 5:101161ATVBAHA122315499.

Taïlé J, Bringart M, Planesse C, Patché J, Rondeau P, Veeren B, Clerc P, Gauvin-Bialecki A, Bourane S, Meilhac O, Couret D, Gonthier MP. Antioxidant Polyphenols of Antirhea borbonica Medicinal Plant and Caffeic Acid Reduce Cerebrovascular, Inflammatory and Metabolic Disorders Aggravated by High-Fat Diet-Induced Obesity in a Mouse Model of Stroke. Antioxidants (Basel). 2022 Apr 27;11(5):858. doi: 10.3390/antiox11050858.

Tanaka S, Thy M, Rozencwajg S, Tran-Dinh A, Montravers P. In severe necrotising soft-tissue infections, do skin defect surfaces matter ? Anaesth Crit Care Pain Med. 2022 Apr 22;41(3):101071.

Andries J, Viranaicken W, Cordonin C, Herrscher C, Planesse C, Roquebert B, Lagrange-Xelot M, El-Kalamouni C, Meilhac O, Mavingui P, Couret D, Gadea G, Despres P. The SARS-CoV-2 spike residues 616/644 and 1138/1169 delineate two antibody epitopes in COVID-19 mRNA COMINARTY vaccine (Pfizer/BioNTech). Sci Rep. 2022 Apr 9;12(1):5999.

Coassin S, Chemello K, Khantalin I, Forer L, Döttelmayer P, Schönherr S, Grüneis R, Chong-Hong-Fong C, Nativel B, Ramin-Mangata S, Gallo A, Roche M, Mühlegger B, Gieger C, Peters A, Zschocke J, Marimoutou C, Meilhac O, Lamina C, Kronenberg F, Blanchard V, Lambert G. Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoproteinemia Associated With Genetically Elevated Cardiovascular Risk. Circ Genom Precis Med. 2022 Apr;15(2):e003489.

Gallo A, Mszar R, Miname MH. Updates on the Use of Subclinical Atherosclerosis to Predict Risk of Cardiovascular Events in Heterozygous Familial Hypercholesterolemia. Curr Atheroscler Rep. 2022 Apr 7.

Peyneau M, de Chaisemartin L, Faille D, Messika J, Mal H, Castier Y, Mordant P, Carrasco JL, Tanaka S, Lortat Jacob B, Ferrari P, Arrault X, Ajzenberg N, Chollet-Martin S, Montravers P, Tran-Dinh A. First Experience With Extracorporeal Cytokine Adsorption Therapy After Lung Transplantation. Transpl Int. 2022 Mar 21;35:10319.

Chemello K, Blom DJ, Marais AD, Lambert G, Blanchard V. Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms. Curr Atheroscler Rep. 2022 Mar 30.

Narra SS, Rosanaly S, Rondeau P, Patche J, Veeren B, Gonthier MP, Viranaicken W, Diotel N, Ravanan P, Hellencourt CL, Meilhac O. ApoA-I Nanoparticles as Curcumin Carriers for Cerebral Endothelial Cells: Improved Cytoprotective Effects against Methylglyoxal. Pharmaceuticals (Basel). 2022 Mar 13;15(3):347.

Tanaka S, Begue F, Veeren B, Tran-Dinh A, Robert T, Tashk P, Lortat-Jacob B, Faille D, de Chaisemartin L, Zappella N, Atchade E, Kramer L, Montravers P, Meilhac O. First Recombinant High-Density Lipoprotein Particles Administration in a Severe ICU COVID-19 Patient, a Multi-Omics Exploratory Investigation. Biomedicines. 2022 Mar 23;10(4):754.

Gence L, Fernezelian D, Bringart M, Veeren B, Christophe A, Brion F, Meilhac O, Bascands JL, Diotel N. Hypericum lanceolatum Lam. Medicinal Plant: Potential Toxicity and Therapeutic Effects Based on a Zebrafish Model. Front Pharmacol. 2022 Mar 11;13:832928.

Thouvenot K, Turpin T, Taïlé J, Clément K, Meilhac O, Gonthier MPC. Links between Insulin Resistance and Periodontal Bacteria: Insights on Molecular Players and Therapeutic Potential of Polyphenols. Biomolecules. 2022 Feb 28;12(3):378.

Croyal M, Wargny M, Chemello K, Chevalier C, Blanchard V, Bigot-Corbel E, Lambert G, Le May C, Hadjadj S, Cariou B. Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes. Cardiovasc Diabetol. 2022 Feb 7;21(1):21.

Tanaka S, Thy M, Khoury R, Tran-Dinh A, Khalil A, Montravers P. Severe necrotizing soft-tissue infection-associated mortality: Have a look at the computed tomography! Crit Care. 2022 Jan 25;26(1):27. doi: 10.1186/s13054-022-03898-1.

Tanaka S, Thy M, Tashk P, Ribeiro L, Lortat-Jacob B, Hermieu JF, Zappella N, Rozencwajg S, Snauwaert A, Atchade E, Grall N, Assadi M, Tran-Dinh A, Montravers P. Impact of prior antibiotic therapy on severe necrotizing soft-tissue infections in ICU patients: results from a French retrospective and observational study. Eur J Clin Microbiol Infect Dis. 2022 Jan;41(1):109-117. doi: 10.1007/s10096-021-04354-8. Epub 2021 Oct 9.

J Bonneville, P Rondeau, B Veeren, J Faccini, MP Gonthier, O Meilhac, Vindis C. Antioxidant and Cytoprotective Properties of Polyphenol-Rich Extracts from Antirhea borbonica and Doratoxylon apetalum against Atherogenic Lipids in Human Endothelial Cells. Antioxidants 2022 11 (1), 34.




Couret D, Planesse C, Patche J, Diotel N, Nativel B, Bourane S, Meilhac O. Lack of Neuroprotective Effects of High-Density Lipoprotein Therapy in Stroke under Acute Hyperglycemic Conditions. Molecules. 2021 Oct 21;26(21):6365. doi: 10.3390/molecules26216365.

Ramlagan P, Issa MY, Rondeau P, Bourdon E, Bahorun T, Farag MA, Neergheen VS. Metabolite Profiling of Antioxidant Rich Fractions of Punica granatum L. Mesocarp and CD36 Expression Regulation. J Am Coll Nutr. 2021 Oct 22:1-19. doi: 10.1080/07315724.2021.1978349.

Zhang G, Lübke L, Chen F, Beil T, Takamiya M, Diotel N, Strähle U, Rastegar S. Neuron-Radial Glial Cell Communication via BMP/Id1 Signaling Is Key to Long-Term Maintenance of the Regenerative Capacity of the Adult Zebrafish Telencephalon. Cells. 2021 Oct 19;10(10):2794. doi: 10.3390/cells10102794.

Bensenor I, Padilha K, Lima IR, Santos RD, Lambert G, Ramin-Mangata S, Bittencourt MS, Goulart AC, Santos IS, Mill JG, Krieger JE, Lotufo PA, Pereira AC.  Genome-Wide Association of Proprotein Convertase Subtilisin/Kexin Type 9 Plasma Levels in the ELSA-Brasil Study. Front Genet. 2021 Sep 29;12:728526. doi: 10.3389/fgene.2021.728526. eCollection 2021.

Zeitlinger M, Bauer M, Reindl-Schwaighofer R, Stoekenbroek RM, Lambert G, Berger-Sieczkowski E, Lagler H, Oesterreicher Z, Wulkersdorfer B, Lührs P, Galabova G, Schwenke C, Mader RM, Medori R, Landlinger C, Kutzelnigg A, Staffler G. A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9. Eur J Clin Pharmacol. 2021 Oct;77(10):1473-1484.

Tanaka S, De Tymowski C, Zappella N, Snauwaert A, Robert T, Lortat-Jacob B, Castier Y, Tran-Dinh A, Tashk P, Bouzid D, Para M, Pellenc Q, Atchade E, Meilhac O, Montravers P. Lipoprotein concentration in patients requiring extracorporeal membrane oxygenation. Sci Rep. 2021 Aug 26;11(1):17225.

Treiber G, Flaus Furmaniuk A, Guilleux A, Medjane S, Bonfanti O, Schneebeli S, Bernard C, Le-Moullec N, Bakiri F, Pholsena M, Rollot O, Vatier C, Jarlet E, Jéru I, Lascols O, Darcel F, Domun B, Venault A, Venault S, Jacquemont ML, Doray B, Maiza JC, Cogne M, Vigouroux C, Nobécourt E. A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA founder variant highlights the multifaceted cardiac manifestations of metabolic laminopathies. Eur J Endocrinol. 2021 Aug 27;185(4):453-462.

Nativel B, Ramin-Mangata S,  Meilhac O, Lambert G, Bourane S. PCSK9 deficiency protects against ischemic stroke but increases hemorrhagic transformation in a hyperglycemic mouse model Atherosclerosis 2021 331:e95.

Heslinga M, Lambert G, Thédrez A, Kastelein J, Nurmohamed MT. Comment on: Proprotein convertase subtilisin/kexin type 9 in the dyslipidaemia of patients with axial spondyloarthritis is related to disease activity. Rheumatology (Oxford). 2021 Aug 2;60(8):e292-e293. doi: 10.1093.

Blanchard V, Chemello K, Hollstein T, Hong-Fong CC, Schumann F, Grenkowitz T, Nativel B, Coassin S, Croyal M, Kassner U, Lamina C, Steinhagen-Thiessen E, Lambert G. The size of apolipoprotein (a) is an independent determinant of the reduction in lipoprotein (a) induced by PCSK9 inhibitors. Cardiovasc Res. 2021 Jul 26:cvab247. doi: 10.1093/cvr/cvab247.

Nativel B, Ramin-Mangata S, Couret D, Planesse C, Roche M, Gallo A, Meilhac O, Lambert G, Bourane S. PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Inhibition in Hyperglycemic Mice Increases the Risk of Hemorrhagic Transformation of Ischemic Stroke. Stroke. 2021 Jul 28:STROKEAHA121035677. doi: 10.1161.

Chemello K, Jaafar AK, Lambert G. Heart to heart with PCSK9. Eur Heart J. 2021 Jul 29:ehab480. doi: 10.1093.

Lecuru M, Nicolas-Chanoine MH, Tanaka S, Montravers P, Armand-Lefevre L, Denamur E, Mammeri H. Emergence of Imipenem Resistance in a CpxA-H208P-Variant-Producing Proteus mirabilis Clinical Isolate. Microb Drug Resist. 2021 Jun;27(6):747-751.

Elmaleh Y, De Tymowski C, Zappella N, Jean-Baptiste S, Tran-Dinh A, Tanaka S, Yung S, Lortat-Jacob B, Mal H, Castier Y, Atchade E, Montravers P. Blood transfusion of the donor is associated with stage 3 primary graft dysfunction after lung transplantation. Clin Transplant. 2021 Jun 26. doi: 10.111.

Rummun N, Serag A, Rondeau P, Ramsaha S, Bourdon E, Bahorun T, Farag MA, Neergheen VS. Antiproliferative activity of Syzygium coriaceum, an endemic plant of Mauritius, with its UPLC-MS metabolite fingerprint: A mechanistic study. PLoS One. 2021 Jun 1;16(6):e0252276.

Turpin C, Catan A,  Meilhac O, Bourdon E, Canonne-Hergaux F, Rondeau P. Erythrocytes: Central Actors in Multiple Scenes of Atherosclerosis Int. J. Mol. Sci. 2021, 22, 5843.

Ghaddar B, Bringart M, Lefebvre d’Hellencourt C, Meilhac O, Diotel N.  Deleterious Effects of Overfeeding on Brain Homeostasis and Plasticity in Adult Zebrafish. Zebrafish. 2021 May 21. doi: 10.1089/zeb.2020.1962.

Lebeau G, Frumence E, Turpin J, Begue F, Hoarau JJ, Gadea G, Krejbich-Trotot P, Desprès P, Viranaicken W. Zika E Glycan Loop Region and Guillain-Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development. Vaccines (Basel). 2021 Mar 19;9(3):283.

Thy M, Tanaka S, Tran-Dinh A, Ribeiro L, Lortat-Jacob B, Donadio J, Zappella N, Ben-Rehouma M, Tashk P, Snauwaert A, Atchade E, Grall N, Montravers P. Dynamic Changes in Microbial Composition During Necrotizing Soft-Tissue Infections in ICU Patients. Front Med (Lausanne). 2021 Mar 4;7:609497.

Ghaddar B, Lübke L, Couret D, Rastegar S, Diotel N. Cellular Mechanisms Participating in Brain Repair of Adult Zebrafish and Mammals after Injury. Cells. 2021 Feb 14;10(2):391. doi: 10.3390/cells10020391.

Merchant N, Garelnabi M, Karabina SA, Meilhac O, Narasimhulu CA, Penumetcha M, Lehner A, Earle D, Song M, Kim JG, Raghavamenon A, Rajagopalan S, Khan BV, Santanam N. Sampath Parthasarathy, PhD, MBA, 1947-2020. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1251-1252.

Zeitlinger M, Bauer M, Reindl-Schwaighofer R, Stoekenbroek RM, Lambert G, Berger-Sieczkowski E, Lagler H, Oesterreicher Z, Wulkersdorfer B, Lührs P, Galabova G, Schwenke C, Mader RM, Medori R, Landlinger C, Kutzelnigg A, Staffler G. A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9. Eur J Clin Pharmacol. 2021 May 10. doi: 10.1007/s00228-021-03149-2.

Grisotto C, Taïlé J, Planesse C, Diotel N, Gonthier MP, Meilhac O, Couret D. High-Fat Diet Aggravates Cerebral Infarct, Hemorrhagic Transformation and Neuroinflammation in a Mouse Stroke Model. Int J Mol Sci. 2021 Apr 27;22(9):4571. doi: 10.3390/ijms22094571. PMID: 33925459

Ramin-Mangata S, Thedrez A, Nativel B, Diotel N, Blanchard V, Wargny M, Aguesse A, Billon-Crossouard S, Vindis C, Le May C, Hulin P, Armanet M, Gmyr V, Pattou F, Croyal M, Meilhac O, Nobécourt E, Cariou B, Lambert G. Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function. Atherosclerosis. 2021 Apr 20:S0021-9150(21)00184-2.

Tailliar M, Schanstra JP, Dierckx T, Breuil B, Hanouna G, Charles N, Bascands JL, Dussol B, Vazi A, Chiche L, Siwy J, Faguer S, Daniel L, Daugas E, Jourde-Chiche N, On Behalf Of The Groupe Coopératif Sur le Lupus Rénal Gclr. Urinary Peptides as Potential Non-Invasive Biomarkers for Lupus Nephritis: Results of the Peptidu-LUP Study. J Clin Med. 2021 Apr 14;10(8):1690. doi: 10.3390/jcm10081690. PMID: 33920017

Keller L, Tardy C, Ligat L, Gilhodes J, Filleron T, Bery N, Rochaix P, Aquilina A, Bdioui S, Roux T, Trinquet E, Favre G, Olichon A.  Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer Anal Chem. 2021 Apr 7. doi: 10.1021/acs.analchem.0c05137.

Veeren B, Bringart M, Turpin C, Rondeau P, Planesse C, Ait-Arsa I, Gimié F, Marodon C, Meilhac O, Gonthier MP, Diotel N, Bascands JL. Caffeic Acid, One of the Major Phenolic Acids of the Medicinal Plant Antirhea borbonica, Reduces Renal Tubulointerstitial Fibrosis. Biomedicines. 2021 Mar 30;9(4):358.

Sulliman NCGhaddar BGence LPatche J, Rastegar S, Meilhac ODiotel N.  HDL biodistribution and brain receptors in zebrafish, using HDLs as vectors for targeting endothelial cells and neural progenitors. Sci Rep. 2021 Mar 19;11(1):6439. doi: 10.1038/s41598-021-85183-9.

Reslan A, Haddad JG, Moukendza Koundi L, Desprès P, Bascands JL, Gadea G. Zika Virus Growth in Human Kidney Cells Is Restricted by an Elevated Glucose Level. Int J Mol Sci. 2021 Mar 2;22(5):2495.

Chemello K, García-Nafría J, Gallo A, Martín C, Lambert G, Blom D. Lipoprotein Metabolism in Familial Hypercholesterolemia. J Lipid Res. 2021 Mar 3:100062. doi: 10.1016/j.jlr.2021.100062.

Zeller M, Lambert G, Farnier M, Maza M, Nativel B, Rochette L, Vergely C, Cottin Y. PCSK9 levels do not predict severity and recurrence of cardiovascular events in patients with acute myocardial infarction. Nutr Metab Cardiovasc Dis. 2021 Mar 10;31(3):880-885.

Klein J, Buffin-Meyer B, Boizard F, Moussaoui N, Lescat O, Breuil B, Fedou C, Feuillet G, Casemayou A, Neau E, Hindryckx A, Decatte L, Levtchenko E, Raaijmakers A, Vayssière C, Goua V, Lucas C, Perrotin F, Cloarec S, Benachi A, Manca-Pellissier MC, Delmas HL, Bessenay L, Le Vaillant C, Allain-Launay E, Gondry J, Boudailliez B, Simon E, Prieur F, Lavocat MP, Saliou AH, De Parscau L, Bidat L, Noel C, Floch C, Bourdat-Michel G, Favre R, Weingertner AS, Oury JF, Baudouin V, Bory JP, Pietrement C, Fiorenza M, Massardier J, Kessler S, Lounis N, Auriol FC, Marcorelles P, Collardeau-Frachon S, Zürbig P, Mischak H, Magalhães P, Batut J, Blader P, Saulnier Blache JS, Bascands JL, Schaefer F, Decramer S, Schanstra JP; BIOMAN consortium. Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease. Kidney Int. 2021 Mar;99(3):737-749.

Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Sci Rep. 2021 Feb 16;11(1):3881.

Ramlagan P, Rondeau P, Neergheen VS, Bourdon E, Bahorun T. The Prophylactic Activity of Punica granatum L. mesocarp Protects Preadipocytes against Ribosylated BSA-Induced Toxicity. J Am Coll Nutr. 2021 Feb 19:1-15.

Huijgen R, Blom DJ, Hartgers ML, Chemello K, Benito-Vicente A, Uribe KB, Behardien Z, Blackhurst DM, Brice BC, Defesche JC, de Jong AG, Jooste RJ, Solomon GAE, Wolmarans KH, Hovingh GK, Martin C, Lambert G, Marais AD. Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):934-943.

Taïlé J, Patché J, Veeren B, Gonthier MP. Hyperglycemic Condition Causes Pro-Inflammatory and Permeability Alterations Associated with Monocyte Recruitment and Deregulated NF κB/PPARg Pathways on Cerebral Endothelial Cells: Evidence for Polyphenols Uptake and Protective Effect. Int J Mol Sci 2021, 22, 1385.

Begue F, Tanaka S, Mouktadi Z, Rondeau P, Veeren B, Diotel N, Tran-Dinh A, Robert T, Vélia E, Mavingui P, Lagrange-Xélot M, Montravers P, Couret D, Meilhac O.Altered high-density lipoprotein composition and functions during severe COVID-19. Sci Rep 2021;11(1):2291.

Checkouri E, Ramin-Mangata S, Diotel N, Viranaicken W, Marodon C, Reignier F, Robert-Da Silva C, Meilhac O. Protective Effects of Medicinal Plant Decoctions on Macrophages in the Context of Atherosclerosis. Nutrients 2021;13(1).

Dobi A, Rosanaly S, Devin A, Baret P, Meilhac O, Harry J, Lefebvre d’Hellencourt C, Rondeau P Advanced glycation end-products disrupt brain microvascular endothelial cell barrier: The role of mitochondria and oxidative stress Microvascular Research, 2021, 133:104098.

Tanaka S, Stern J, Bouzid D, Robert T, Dehoux M, Snauwaert A, Zappella N, Cournot M, Lortat-Jacob B, Augustin P, Atchade E, Tran-Dinh A, Meilhac O, Montravers P. Relationship between lipoprotein concentrations and short-term and 1-year mortality in intensive care unit septic patients: results from the HIGHSEPS study. Ann Intensive Care 2021;11(1):11.

Gatto G, Bourane S, Ren X, Di Costanzo S, Fenton PK, Halder P, Seal RP, Goulding MD. A Functional Topographic Map for Spinal Sensorimotor Reflexes. Neuron 2021;109(1):91-104 e5.


Checkouri E, Reignier F, Robert-Da Silva C, Meilhac O. Evaluation of Polyphenol Content and Antioxidant Capacity of Aqueous Extracts from Eight Medicinal Plants from Reunion Island: Protection against Oxidative Stress in Red Blood Cells and Preadipocytes. Antioxidants (Basel) 2020;9(10).

Guerin M, Robert-Da Silva C, Garcia C and Remize F. Lactic Acid Bacterial Production of Exopolysaccharides from Fruit and Vegetables and Associated Benefits. Fermentation 2020, 6(4), 115.

Rummun N, Rondeau P, Bourdon E, Pires E, McCullagh J, Claridge TDW, Bahorun T, Li WW, Neergheen VS. Terminalia bentzoë, a Mascarene Endemic Plant, Inhibits Human Hepatocellular Carcinoma Cells Growth In Vitro via G0/G1 Phase Cell Cycle Arrest Pharmaceuticals 2020 13 (10), 303.

Ghaddar B, Veeren B, Rondeau P, Bringart M, Lefebvre d’Hellencourt C, Meilhac O, Bascand, J L and Diotel N., Impaired brain homeostasis and neurogenesis in diet-induced overweight zebrafish: a preventive role from A. borbonica extract, Sci Rep, 2020, 10: 14496.

Veeren B, Ghaddar B, Bringart M, Khazaal S, Gonthier MP, Meilhac O, Diotel N, Bascands JL. Phenolic Profile of Herbal Infusion and Polyphenol-Rich Extract from Leaves of the Medicinal Plant Antirhea borbonica: Toxicity Assay Determination in Zebrafish Embryos and Larvae. Molecules. 2020 Sep 29;25(19):4482. doi: 10.3390/molecules25194482.

Haddad, J. G., Grauzdyte, D., Koishi, A. C., Viranaicken, W., Venskutonis, P. R., Nunes Duarte Dos Santos, C., Despres, P., Diotel, N. and El Kalamouni, C., The Geraniin-Rich Extract from Reunion Island Endemic Medicinal Plant Phyllanthus phillyreifolius Inhibits Zika and Dengue Virus Infection at Non-Toxic Effect Doses in Zebrafish, Molecules, 2020, 25.

Perdomo, L., Vidal-Gomez, X., Soleti, R., Vergori, L., Duluc, L., Chwastyniak, M., Bisserier, M., Le Lay, S., Villard, A., Simard, G., Meilhac, O., Lezoualc’h, F., Khantalin, I., Veerapen, R., Dubois, S., Boursier, J., Henni, S., Gagnadoux, F., Pinet, F., Andriantsitohaina, R. and Martinez, M. C., Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis, Circ Res, 2020, 127: 747-760.

Varela LM, Meseguer E, Lapergue B, Couret D, Amarenco P and Meilhac O, Changes in High-Density Lipoproteins Related to Outcomes in Patients with Acute Stroke, J Clin Med, 2020, 9.

Zhang, G., Ferg, M., Lubke, L., Takamiya, M., Beil, T., Gourain, V., Diotel, N., Strahle, U. and Rastegar, S., Bone morphogenetic protein signaling regulates Id1-mediated neural stem cell quiescence in the adult zebrafish brain via a phylogenetically conserved enhancer module, Stem Cells, 2020.

Chemello K., Beeske, S., Trang Tran, T. T., Blanchard, V., Villard, E. F., Poirier, B., Le Bail, J. C., Dargazanli, G., Ho-Van-Guimbal, S., Boulay, D., Bergis, O., Pruniaux, M. P., Croyal, M., Janiak, P., Guillot, E. and Lambert, G., Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab, JACC Basic Transl Sci, 2020, 5: 549-557.

Cordonin, C., Turpin, M., Bringart, M., Bascands, J. L., Flores, O., Dellagi, K., Mavingui, P., Roche, M. and Tortosa, P., Pathogenic Leptospira and their animal reservoirs: testing host specificity through experimental infection, Sci Rep, 2020, 10: 7239.

Logre, E., Enser, M., Tanaka, S., Dubert, M., Claudinon, A., Grall, N., Mentec, H., Montravers, P. and Pajot, O., Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database, Ann Intensive Care, 2020, 10: 75.

Magalhaes, E., Reuter, J., Wanono, R., Bouadma, L., Jaquet, P., Tanaka, S., Sinnah, F., Ruckly, S., Dupuis, C., de Montmollin, E., Para, M., Braham, W., Pisani, A., d’Ortho, M. P., Rouvel-Tallec, A., Timsit, J. F. and Sonneville, R., Early EEG for Prognostication Under Venoarterial Extracorporeal Membrane Oxygenation, Neurocrit Care, 2020.

Septembre-Malaterre, A., Lalarizo Rakoto, M., Marodon, C., Bedoui, Y., Nakab, J., Simon, E., Hoarau, L., Savriama, S., Strasberg, D., Guiraud, P., Selambarom, J. and Gasque, P., Artemisia annua, a Traditional Plant Brought to Light, Int J Mol Sci, 2020, 21.

Turpin, J., Frumence, E., El Safadi, D., Meilhac, O., Krejbich-Trotot, P. and Viranaicken, W., Improvement of immunodetection of the transcription factor C/EBP homologous protein by western blot, Anal Biochem, 2020, 601: 113775.

Ramlagan P, Rondeau P, Neergheen-Bhujun VS,  Bourdon E, Bahorun T. The prophylactic activity of Punica granatum L. mesocarp protects preadipocytes against ribosylated BSA-induced toxicity.J Am Coll Nutr 2020

Turpin C, Catan A, Guerin-Dubourg A, Debussche X, Bravo SB, Alvarez E, Van Den Elsen J, Meilhac O, Rondeau P, Bourdon E.  Enhanced oxidative stress and damage in glycated erythrocytes. PLoS One 2020 15:e0235335.

Omarjee L, Meilhac O, Perrot F, Janin A, Mahe G.  Can Ticagrelor be used to prevent sepsis-induced coagulopathy in COVID-19? Clin Immunol 2020 216:108468.

Taile J, Arcambal A, Clerc P, Gauvin-Bialecki A, Gonthier MP. Medicinal Plant Polyphenols Attenuate Oxidative Stress and Improve Inflammatory and Vasoactive Markers in Cerebral Endothelial Cells during Hyperglycemic Condition Antioxidants (Basel) 2020 9(7), 573

Ledard N, Liboz A, Blondeau B, Babiak M, Moulin C, Vallin B, Guillas I, Mateo V, Jumeau C, Blirando K, Meilhac O, Limon I, Glorian M. Slug, a Cancer-Related Transcription Factor, is Involved in Vascular Smooth Muscle Cell Transdifferentiation Induced by Platelet-Derived Growth Factor-BB During Atherosclerosis. J Am Heart Assoc 2020 9:e014276.

Arcambal A, Taile J, Couret D, Planesse C, Veeren B, Diotel N, Gauvin-Bialecki A, Meilhac O, Gonthier MP. Protective Effects of Antioxidant Polyphenols against Hyperglycemia-Mediated Alterations in Cerebral Endothelial Cells and a Mouse Stroke Model. Mol Nutr Food Res 2020 :e1900779.

Omarjee L, Janin A, Perrot F, Laviolle B, Meilhac O, Mahe G.  Targeting T-cell senescence and cytokine storm with rapamycin to prevent severe progression in COVID-19. Clin Immunol 2020 216:108464.

Atchade E, Desmard M, Kantor E, Geneve C, Tebano G, De Tymowski C, Tran-Dinh A, Zappella N, Houze S, Mal H, Castier Y, Tanaka S, Montravers P.  Fungal Isolation in Respiratory Tract After Lung Transplantation: Epidemiology, Clinical Consequences, and Associated Factors. Transplant Proc 2020 52:326-332.

Blanchard V, Garcon D, Jaunet C, Chemello K, Billon-Crossouard S, Aguesse A, Garfa A, Famchon G, Torres A, Le May C, Pichelin M, Bigot-Corbel E, Lambert G, Cariou B, Hadjadj S, Krempf M, Bach-Ngohou K, Croyal M. A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins. 2020 J Lipid Res.

Croyal M, Blanchard V, Ouguerram K, Chetiveaux M, Cabioch L, Moyon T, Billon-Crossouard S, Aguesse A, Bernardeau K, Le May C, Flet L, Lambert G, Hadjadj S, Cariou B, Krempf M, Nobecourt-Dupuy E. VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly. Arterioscler Thromb Vasc Biol 2020 40:819-829.

Delveaux J, Turpin C, Veeren B, Diotel N, Bravo SB, Begue F, Alvarez E, Meilhac O, Bourdon E, Rondeau P.  Antirhea borbonica Aqueous Extract Protects Albumin and Erythrocytes from Glycoxidative Damages. Antioxidants (Basel) 2020 9(5): 415.

Evison BJ, Palmer JT, Lambert G, Treutlein H, Zeng J, Nativel B, Chemello K, Zhu Q, Wang J, Teng Y, Tang W, Xu Y, Rathi AK, Kumar S, Suchowerska AK, Parmar J, Dixon I, Kelly GE, Bonnar J.  A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorg Med Chem 2020 28:115344.

Meilhac O, Tanaka S, Couret D.  High-Density Lipoproteins Are Bug Scavengers. Biomolecules 2020 10(4): 598.

Ramin-Mangata S, Wargny M, Pichelin M, Le May C, Thedrez A, Blanchard V, Nativel B, Santos RD, Bensenor IM, Lotufo PA, Lambert G, Cariou B.  Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes. Atherosclerosis 2020 293:49-56.

Ruskovska T, Massaro M, Carluccio MA, Arola-Arnal A, Muguerza B, Vanden Berghe W, Declerck K, Bravo FI, Calabriso N, Combet E, Gibney ER, Gomes A, Gonthier MP, Kistanova E, Krga I, Mena P, Morand C, Nunes Dos Santos C, de Pascual-Teresa S, Rodriguez-Mateos A, Scoditti E, Suarez M, Milenkovic D. Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease. Food Funct 2020.

Tanaka S, Couret D, Tran-Dinh A, Duranteau J, Montravers P, Schwendeman A, Meilhac O.  High-density lipoproteins during sepsis: from bench to bedside. Crit Care 2020 24:134.

Tanaka S, Geneve C, Zappella N, Yong-Sang J, Planesse C , Louedec L, Viranaicken W, Bringart M, Montravers P, Denamur E, Duranteau J, Couret D, Meilhac O. Reconstituted High-density Lipoprotein Therapy Improves Survival in Mouse Models of Sepsis. Anesthesiology 2020 132:825-838.




Catan A, Turpin C, Diotel N, Patche J, Guerin-Dubourg A, Debussche X, Bourdon E, Ah-You N, Le Moullec N, Besnard M, Veerapen R, Rondeau P, Meilhac O. (2019) Aging and glycation promote erythrocyte phagocytosis by human endothelial cells: Potential impact in atherothrombosis under diabetic conditions. Atherosclerosis. 2019 Oct 26;291:87-98.

Haddad JG, Picard M, Bénard S, Desvignes C, Desprès P,Diotel N, El Kalamouni C. (2019) Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish. Molecules. 2019 Sep 23;24(19).

Augustin P, Tran-Dinh A, Desmard M, Tanaka S, Grall N, Ben-Rehouma M, Arapis K, Ribeiro-Parenti L, Montravers P. (2019) Usefulness of Gram stain examination of peritoneal fluid in postoperative peritonitis to guide empirical antibiotherapy. Eur J Trauma Emerg Surg. 2019 May 29.

Tanaka S, Diallo D, Delbosc S, Genève C, Zappella N, Yong-Sang J, Patche J, Harrois A, Hamada S, Denamur E, Montravers P, Duranteau J, Meilhac O. (2019) High-density lipoprotein (HDL) particle size and concentration changes in septic shock patients. Ann Intensive Care. 2019 Jun 13;9(1):68.

Guibbal F, Meneyrol V, Ait-Arsa I, Diotel N, Patché J, Veeren B, Bénard S, Gimié F, Yong-Sang J, Khantalin I, Veerapen R, Jestin E, Meilhac O (2019) Synthesis and Automated Labeling of [18F]Darapladib, a Lp-PLA2 Ligand, as Potential PET Imaging Tool of Atherosclerosis.ACS Med Chem Lett. 2019 Apr 4;10(5):743-748.

Yong-Sang J, Dioury F, Meneyrol V, Ait-Arsa I, Idoumbin JP, Guibbal F, Patché J, Gimié F, Khantalin I, Couprie J, Giraud P, Benard S, Ferroud C, Jestin E, Meilhac O. (2019) Development, synthesis, and 68Ga-Labeling of a Lipophilic complexing agent for atherosclerosis PET imaging. Eur J Med Chem. 2019 Aug 15;176:129-134.

Augustin P, Guivarch E, Tran-Dinh A, Pellenc Q, Tanaka S, Montravers P. (2019) Usefulness of CT-scan in the management of chest stab trauma: a prospective observational study. Eur J Trauma Emerg Surg. 2019 Aug 12.

Youssouf L, Bhaw-Luximon A, Diotel N, Catan A, Giraud P, Gimié F, Koshel D, Casale S, Bénard S, Meneyrol V, Lallemand L, Meilhac O, Lefebvre D’Hellencourt C, Jhurry D, Couprie J (2019) Enhanced effects of curcumin encapsulated in polycaprolactone-grafted oligocarrageenan nanomicelles, a novel nanoparticle drug delivery system.Carbohydr Polym. 2019 Aug 1;217:35-45.

Lopatko Fagerström I, Ståhl AL, Mossberg M, Tati R, Kristoffersson AC, Kahn R, Bascands JL, Klein J, Schanstra JP, Segelmark M, Karpman D. Blockade of the kallikrein-kinin system reduces endothelial complement activation in vascular inflammation. EBioMedicine. 2019 Sep;47:319-328.

Vinel C, Schanstra JP, Boizard F, Péreira O, Auriau J, Dortignac A, Breuil B, Feuillet G, Nkuipou-Kenfack E, Zürbig P, Valet P, Bascands JL, Dray C, Denis C. Apelin affects the mouse aging urinary peptidome with minimal effects on kidney. Sci Rep. 2019 Jul 23;9(1):10647.

Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C, Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J. Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight. 2019 May 16;4(10). pii: 125638.

Meilhac O. (2019) High-density Lipoproteins (HDLs): Biomarkers or bio-actors of abdominal aortic aneurysmal disease ? EBioMedicine. 2019 May;43:5-6.

Chemello K, Martín C, Lambert G. (2019) PCSK9 inhibition for autosomal recessive hypercholesterolemia. Atherosclerosis. 2019 May;284:209-211.

Khantalin I, Blanchard V, Viallet N, Lambert G. (2019) Recurrent coronary syndromes in a patient with isolated very-high lipoprotein (a) and the prothrombin genetic variant rs1799963 (G20210A): a case report. Eur Heart J Case Rep. 2019 Feb 25;3(1):ytz019.

Cordonin C, Turpin M, Bascands JL, Dellagi K, Mavingui P, Tortosa P, Roche M. Three Leptospira Strains From Western Indian Ocean Wildlife Show Highly Distinct Virulence Phenotypes Through Hamster Experimental Infection. Front Microbiol. 2019 Mar 11;10:382.

Mokou M, Klein J, Makridakis M, Bitsika V, Bascands JL, Saulnier-Blache JS, Mullen W, Sacherer M, Zoidakis J, Pieske B, Mischak H, Roubelakis MG, Schanstra JP, Vlahou A. Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease. EBioMedicine. 2019 Mar;41:91-104.

Arcambal, A., Taile, J., Rondeau, P., Viranaicken, W., Meilhac, O., and Gonthier, M. P. (2019) Hyperglycemia modulates redox, inflammatory and vasoactive markers through specific signaling pathways in cerebral endothelial cells: insights on insulin protective action. Free Radic Biol Med 130, 59-70 – Pubmed

Blanchard, V., Khantalin, I., Ramin-Mangata, S., Chemello, K., Nativel, B., and Lambert, G. (2019) PCSK9: from biology to clinical applications. Pathology 51, 177-183.

Nativel B, Ramin-Mangata S, Mevizou R, Figuester A, Andries J, Iwema T, Ikewaki N, Gasque P, Viranaïcken W. (2019) CD93 is a cell surface lectin receptor involved in the control of the inflammatory response stimulated by exogenous DNA. Immunology  2019 Oct;158(2):85-93.

Billet S, Pugnet G, Chollet T, Charbonnier G, Fournier P, Prévot G, Tetu L, Cournot M, Derumeaux H, Carrié D, Galinier M, Lairez O. (2019) The Use of Transthoracic Echocardiogram to Quantify Pulmonary Vascular Resistance in Patients with Systemic Sclerosis. J Rheumatol. 2019 Nov;46(11):1495-1501.

Couret, D., Simeone, P., Freppel, S., and Velly, L. (2019) The effect of ambient-light conditions on quantitative pupillometry: a history of rubber cup. Neurocrit Care 2019 Apr;30(2):492-493.

Chabert M, Rousset X, Colombat M, Lacasa M, Kakanakou H, Bourderioux M, Brousset P, Burlet-Schiltz O, Liepnieks JJ, Kluve-Beckerman B, Lambert G, Châtelet FP, Benson MD, Kalopissis AD. (2019) A transgenic mouse model reproduces human hereditary systemic amyloidosis.Kidney Int. 2019 Sep;96(3):628-641.

Rastegar S, Parimisetty A, Cassam Sulliman N, Narra SS, Weber S, Rastegar M, Viranaicken W, Couret D, Planesse C, Strähle U, Meilhac O, Lefebvre d’Hellencourt C, Diotel N (2019) Expression of adiponectin receptors in the brain of adult zebrafish and mouse: Links with neurogenic niches and brain repair. J Comp Neurol. 2019 Oct 1;527(14):2317-2333.



Weger, M., Diotel, N., Weger, B. D., Beil, T., Zaucker, A., Eachus, H. L., Oakes, J. A., do Rego, J. L., Storbeck, K. H., Gut, P., Strahle, U., Rastegar, S., Muller, F., and Krone, N. (2018) Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co-factors in zebrafish. J Neuroendocrinol 30, e12586.

Thedrez, A., Blom, D. J., Ramin-Mangata, S., Blanchard, V., Croyal, M., Chemello, K., Nativel, B., Pichelin, M., Cariou, B., Bourane, S., Tang, L., Farnier, M., Raal, F. J., and Lambert, G. (2018) Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab. Arterioscler Thromb Vasc Biol 38, 592-598.

Stoekenbroek, R. M., Lambert, G., Cariou, B., and Hovingh, G. K. (2018) Inhibiting PCSK9 – biology beyond LDL control. Nat Rev Endocrinol 15, 52-62.

Nativel, M., Schneider, F., Saulnier, P. J., Gand, E., Ragot, S., Meilhac, O., Rondeau, P., Burillo, E., Cournot, M., Potier, L., Velho, G., Marre, M., Roussel, R., Rigalleau, V., Mohammedi, K., and Hadjadj, S. (2018) Prognostic Values of Inflammatory and Redox Status Biomarkers on the Risk of Major Lower-Extremity Artery Disease in Individuals With Type 2 Diabetes. Diabetes Care 41, 2162-2169.

Montravers, P., Tran-Dinh, A., and Tanaka, S. (2018) The role of omadacycline in skin and soft tissue infections. Curr Opin Infect Dis 31, 148-154.

Guibbal, F., Benard, S., Patche, J., Meneyrol, V., Couprie, J., Yong-Sang, J., Meilhac, O., and Jestin, E. (2018) Regioselectivity of thiouracil alkylation: Application to optimization of Darapladib synthesis. Bioorganic & medicinal chemistry letters 28, 787-792.

Garcia, C., Montee, N., Faccini, J., Series, J., Meilhac, O., Cantero, A. V., Le Faouder, P., Elbaz, M., Payrastre, B., and Vindis, C. (2018) Acute Coronary Syndrome remodels the antiplatelet aggregation properties of high-density lipoprotein particle subclasses. J Thromb Haemost.

Gajahi Soudahome, A., Catan, A., Giraud, P., Assouan Kouao, S., Guerin-Dubourg, A., Debussche, X., Le Moullec, N., Bourdon, E., Bravo, S. B., Paradela-Dobarro, B., Alvarez, E., Meilhac, O., Rondeau, P., and Couprie, J. (2018) Glycation of human serum albumin impairs binding to the glucagon-like peptide-1 analogue liraglutide. J Biol Chem 293, 4778-4791.

Croyal, M., Tran, T. T., Blanchard, R. H., Le Bail, J. C., Villard, E. F., Poirier, B., Aguesse, A., Billon-Crossouard, S., Ramin-Mangata, S., Blanchard, V., Nativel, B., Chemello, K., Khantalin, I., Thedrez, A., Janiak, P., Krempf, M., Boixel, C., Lambert, G., and Guillot, E. (2018) PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate. Clin Sci (Lond) 132, 1075-1083.

Croyal, M., Kaabia, Z., Leon, L., Ramin-Mangata, S., Baty, T., Fall, F., Billon-Crossouard, S., Aguesse, A., Hollstein, T., Sullivan, D. R., Nobecourt, E., Lambert, G., and Krempf, M. (2018) Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD? Diabetes Metab 44, 143-149.

Saulnier-Blache JS, Wilson R, Klavins K, Graham D, Alesutan I, Kastenmüller G, Wang-Sattler R, Adamski J, Roden M, Rathmann W, Seissler J, Meisinger C, Koenig W, Thiery J, Suhre K, Peters A, Kuro-O M, Lang F, Dallmann G, Delles C, Voelkl J, Waldenberger M, Bascands JL, Klein J, Schanstra JP. (2018) Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease. Atherosclerosis. 2018 Sep;276:140-147.

Buffin-Meyer B, Klein J, Breuil B, Muller F, Moulos P, Groussolles M, Bouali O, Bascands JL, Decramer S, Schanstra JP. (2018) Combination of the fetal urinary metabolome and peptidome for the prediction of postnatal renal outcome in fetuses with PUV. J Proteomics. 2018 Jul 30;184:1-9.

Croyal, M., Billon-Crossouard, S., Goulitquer, S., Aguesse, A., Leon, L., Fall, F., Chetiveaux, M., Moyon, T., Blanchard, V., Ouguerram, K., Lambert, G., Nobecourt, E., and Krempf, M. (2018) Stable Isotope Kinetic Study of ApoM (Apolipoprotein M). Arterioscler Thromb Vasc Biol 38, 255-261.

Cournot, M., Lairez, O., and Medzech, B. (2018) [Preeclampsia: A challenge also for cardiologists]. Ann Cardiol Angeiol (Paris) 67, 280-287.

Cournot, M., Burillo, E., Saulnier, P. J., Planesse, C., Gand, E., Rehman, M., Ragot, S., Rondeau, P., Catan, A., Gonthier, M. P., Feigerlova, E., Meilhac, O., and Hadjadj, S. (2018) Circulating Concentrations of Redox Biomarkers Do Not Improve the Prediction of Adverse Cardiovascular Events in Patients With Type 2 Diabetes Mellitus. J Am Heart Assoc 7.

López-Cayuqueo KI, Chavez-Canales M, Pillot A, Houillier P, Jayat M, Baraka-Vidot J, Trepiccione F, Baudrie V, Büsst C, Soukaseum C, Kumai Y, Jeunemaître X, Hadchouel J, Eladari D, Chambrey R. (2019) A mouse model of pseudohypoaldosteronism type II reveals a novel mechanism of renal tubular acidosis. Kidney Int. 2018 Sep;94(3):514-523.

Couret, D., Bourane, S., Catan, A., Nativel, B., Planesse, C., Dorsemans, A. C., Ait-Arsa, I., Cournot, M., Rondeau, P., Patche, J., Tran-Dinh, A., Lambert, G., Diotel, N., and Meilhac, O. (2018) A hemorrhagic transformation model of mechanical stroke therapy with acute hyperglycemia in mice. J Comp Neurol 526, 1006-1016.

Bohli, N., Meilhac, O., Rondeau, P., Gueffrache, S., Mora, L., and Abdelghani, A. (2018) A facile route to glycated albumin detection. Talanta 184, 507-512.

Blanchard, V., Ramin-Mangata, S., Billon-Crossouard, S., Aguesse, A., Durand, M., Chemello, K., Nativel, B., Flet, L., Chetiveaux, M., Jacobi, D., Bard, J. M., Ouguerram, K., Lambert, G., Krempf, M., and Croyal, M. (2018) Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study. J Lipid Res 59, 892-900.

Arsenault, B. J., Petrides, F., Tabet, F., Bao, W., Hovingh, G. K., Boekholdt, S. M., Ramin-Mangata, S., Meilhac, O., DeMicco, D., Rye, K. A., Waters, D. D., Kastelein, J. J. P., Barter, P., and Lambert, G. (2018) Effect of atorvastatin, cholesterol ester transfer protein inhibition, and diabetes mellitus on circulating proprotein subtilisin kexin type 9 and lipoprotein(a) levels in patients at high cardiovascular risk. J Clin Lipidol 12, 130-136.

Gellens R, Habchi S, Freppel S, Couret D, Iacobelli S. (2018) Romiplostim for the Emergency Management of Severe Immune Thrombocytopenia with Intracerebral Hemorrhage. Front Neurol 8,737.

El Kalamouni C, Frumence E, Bos S, Turpin J, Nativel B., Harrabi W, Wilkinson DA, Meilhac O., Gadea G, Despres P, Krejbich-Trotot, P., and Viranaicken, W. (2018) Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus. Viruses 11(1).


Youssouf, L., Lallemand, L., Giraud, P., Soule, F., Bhaw-Luximon, A., Meilhac, O., D’Hellencourt, C. L., Jhurry, D., and Couprie, J. (2017) Ultrasound-assisted extraction and structural characterization by NMR of alginates and carrageenans from seaweeds. Carbohydr Polym 166, 55-63

Weger, M., Diotel, N., Dorsemans, A. C., Dickmeis, T., and Weger, B. D. (2017) Stem cells and the circadian clock. Dev Biol 431, 111-123

Viranaicken, W., Nativel, B., Krejbich-Trotot, P., Harrabi, W., Bos, S., El Kalamouni, C., Roche, M., Gadea, G., and Despres, P. (2017) ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens. Biochimie 142, 179-182

Trepiccione, F., Prosperi, F., de la Motte, L. R., Hubner, C. A., Chambrey, R., Eladari, D., and Capasso, G. (2017) New Findings on the Pathogenesis of Distal Renal Tubular Acidosis. Kidney Dis (Basel) 3, 98-105

Tarnus, E., Baraka Vidot, J., Dorsemans, A. C., and Bourdon, E. (2017) What is the scale on my histological drawings? A blood tip at La Reunion Island university. Arch Med Biomed Res 3, 112-113

Tanaka, S., Labreuche, J., Drumez, E., Harrois, A., Hamada, S., Vigue, B., Couret, D., Duranteau, J., and Meilhac, O. (2017) Low HDL levels in sepsis versus trauma patients in intensive care unit. Ann Intensive Care 7, 60

Somanah, J., Bourdon, E., and Bahorun, T. (2017) Extracts of Mauritian Carica papaya (var. solo) protect SW872 and HepG2 cells against hydrogen peroxide induced oxidative stress. J Food Sci Technol 54, 1917-1927

Saulnier-Blache, J. S., Feigerlova, E., Halimi, J. M., Gourdy, P., Roussel, R., Guerci, B., Dupuy, A., Bertrand-Michel, J., Bascands, J. L., Hadjadj, S., and Schanstra, J. P. (2017) Urinary lysophopholipids are increased in diabetic patients with nephropathy. J Diabetes Complications 31, 1103-1108

Ribes, D., Casemayou, A., El Hachem, H., Laurent, C., Guilbeau-Frugier, C., Vergez, F., Tavitian, S., Schanstra, J. P., Chauveau, D., Bascands, J. L., Ysebaert, L., and Faguer, S. (2017) Asymptomatic circulating T-cell clone cause renal polymorphic inflammatory fibrosis. Clin Exp Nephrol 21, 781-786

Ramlagan, P., Rondeau, P., Planesse, C., Neergheen-Bhujun, V. S., Bourdon, E., and Bahorun, T. (2017) Comparative suppressing effects of black and green teas on the formation of advanced glycation end products (AGEs) and AGE-induced oxidative stress. Food Funct 8, 4194-4209

Ramlagan, P., Planesse, C., Rondeau, P., Neergheen-Bhujuna, V., Bourdon, E., and Bahorun, T. (2017) Punica granatum L. Mesocarp Extract Suppresses Advanced Glycation End Products (AGEs)- and H2O2-Induced  Oxidative stress and Pro-inflammatory Biomarkers  Journal of Functional Foods 29, 115-126

Patche, J., Girard, D., Catan, A., Boyer, F., Dobi, A., Planesse, C., Diotel, N., Guerin-Dubourg, A., Baret, P., Bravo, S. B., Paradela-Dobarro, B., Alvarez, E., Essop, M. F., Meilhac, O., Bourdon, E., and Rondeau, P. (2017) Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin. Free Radic Biol Med 102, 133-148

Papadopoulos, T., Casemayou, A., Neau, E., Breuil, B., Caubet, C., Calise, D., Thornhill, B. A., Bachvarova, M., Belliere, J., Chevalier, R. L., Moulos, P., Bachvarov, D., Buffin-Meyer, B., Decramer, S., Auriol, F. C., Bascands, J. L., Schanstra, J. P., and Klein, J. (2017) Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction. BMC Syst Biol 11, 31

Paganin, F., Mangiapan, G., Proust, A., Prudhomme, A., Attia, J., Marchand-Adam, S., Pellet, F., Milhe, F., Melloni, B., Bernady, A., Raspaud, C., Nocent, C., Berger, P., and Guilleminault, L. (2017) Lung function parameters in omalizumab responder patients: An interesting tool? Allergy 72, 1953-1961

Nobecourt, E., Cariou, B., Lambert, G., and Krempf, M. (2017) Severe decrease in high-density lipoprotein cholesterol with the combination of fibrates and ezetimibe: A case series. J Clin Lipidol 11, 289-293

Nkuipou-Kenfack, E., Schanstra, J. P., Bajwa, S., Pejchinovski, M., Vinel, C., Dray, C., Valet, P., Bascands, J. L., Vlahou, A., Koeck, T., Borries, M., Busch, H., Bechtel-Walz, W., Huber, T. B., Rudolph, K. L., Pich, A., Mischak, H., and Zurbig, P. (2017) The use of urinary proteomics in the assessment of suitability of mouse models for ageing. PLoS One 12, e0166875

Nativel, B., Couret, D., Giraud, P., Meilhac, O., d’Hellencourt, C. L., Viranaicken, W., and Da Silva, C. R. (2017) Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human. Sci Rep 7, 15789

Mumtaz, R., Trepiccione, F., Hennings, J. C., Huebner, A. K., Serbin, B., Picard, N., Ullah, A., Paunescu, T. G., Capen, D. E., Lashhab, R. M., Mouro-Chanteloup, I., Alper, S. L., Wagner, C. A., Cordat, E., Brown, D., Eladari, D., and Hubner, C. A. (2017) Intercalated Cell Depletion and Vacuolar H(+)-ATPase Mistargeting in an Ae1 R607H Knockin Model. J Am Soc Nephrol 28, 1507-1520

Mirzoyan, K., Klavins, K., Koal, T., Gillet, M., Marsal, D., Denis, C., Klein, J., Bascands, J. L., Schanstra, J. P., and Saulnier-Blache, J. S. (2017) Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia. Biochem Biophys Res Commun 487, 109-115

Mirzoyan, K., Denis, C., Casemayou, A., Gilet, M., Marsal, D., Goudouneche, D., Faguer, S., Bascands, J. L., Schanstra, J. P., and Saulnier-Blache, J. S. (2017) Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury. Inflammation 40, 1707-1716

Mapanga, R. F., Joseph, D. E., Saieva, M., Boyer, F., Rondeau, P., Bourdon, E., and Essop, M. F. (2017) Glycation abolishes the cardioprotective effects of albumin during ex vivo ischemia-reperfusion. Physiol Rep 5

Louet, M., Bitam, S., Bakouh, N., Bignon, Y., Planelles, G., Lagorce, D., Miteva, M. A., Eladari, D., Teulon, J., and Villoutreix, B. O. (2017) In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening. Sci Rep 7, 7249

Le Sage, F., Meilhac, O., and Gonthier, M. P. (2017) Porphyromonas gingivalis lipopolysaccharide induces pro-inflammatory adipokine secretion and oxidative stress by regulating Toll-like receptor-mediated signaling pathways and redox enzymes in adipocytes. Mol Cell Endocrinol 446, 102-110

Le Sage, F., Meilhac, O., and Gonthier, M. P. (2017) Anti-inflammatory and antioxidant effects of polyphenols extracted from Antirhea borbonica medicinal plant on adipocytes exposed to Porphyromonas gingivalis and Escherichia coli lipopolysaccharides. Pharmacol Res 119, 303-312

Lambert, G., Thedrez, A., Croyal, M., Ramin-Mangata, S., Couret, D., Diotel, N., Nobecourt-Dupuy, E., Krempf, M., LeBail, J. C., Poirier, B., Blankenstein, J., Villard, E. F., and Guillot, E. (2017) The complexity of lipoprotein (a) lowering by PCSK9 monoclonal antibodies. Clin Sci (Lond) 131, 261-268

Krochmal, M., Kontostathi, G., Magalhaes, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J. L., Denis, C., Zoidakis, J., Zurbig, P., Delles, C., Schanstra, J. P., Mischak, H., and Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Sci Rep 7, 15160

Krishnan, D., Pan, W., Beggs, M. R., Trepiccione, F., Chambrey, R., Eladari, D., Cordat, E., Dimke, H., and Alexander, R. T. (2017) Deficiency of Carbonic Anhydrase II Results in a Urinary Concentrating Defect. Front Physiol 8, 1108

Guilleminault, L., and Viala-Gastan, C. (2017) [Blomia tropicalis: A house dust mite in the tropics]. Rev Mal Respir 34, 791-801

Guerin-Dubourg, A., Cournot, M., Planesse, C., Debussche, X., Meilhac, O., Rondeau, P., and Bourdon, E. (2017) Association between Fluorescent Advanced Glycation End-Products and Vascular Complications in Type 2 Diabetic Patients. Biomed Res Int 2017, 7989180

Fessard, A., Kapoor, A., Patche, J., Assemat, S., Hoarau, M., Bourdon, E., Bahorun, T., and Remize, F. (2017) Lactic Fermentation as an Efficient Tool to Enhance the Antioxidant Activity of Tropical Fruit Juices and Teas. Microorganisms 5

Dorsemans, A. C., Soule, S., Weger, M., Bourdon, E., Lefebvre d’Hellencourt, C., Meilhac, O., and Diotel, N. (2017) Impaired constitutive and regenerative neurogenesis in adult hyperglycemic zebrafish. J Comp Neurol 525, 442-458

Dorsemans, A. C., Lefebvre d’Hellencourt, C., Ait-Arsa, I., Jestin, E., Meilhac, O., and Diotel, N. (2017) Acute and Chronic Models of Hyperglycemia in Zebrafish: A Method to Assess the Impact of Hyperglycemia on Neurogenesis and the Biodistribution of Radiolabeled Molecules. J Vis Exp

Dorsemans, A. C., Couret, D., Hoarau, A., Meilhac, O., Lefebvre d’Hellencourt, C., and Diotel, N. (2017) Diabetes, adult neurogenesis and brain remodeling: New insights from rodent and zebrafish models. Neurogenesis (Austin) 4, e1281862

Diotel, N., Merot, Y., Coumailleau, P., Gueguen, M. M., Serandour, A. A., Salbert, G., and Kah, O. (2017) 5-hydroxymethylcytosine marks postmitotic neural cells in the adult and developing vertebrate central nervous system. J Comp Neurol 525, 478-497

Croyal, M., Kaabia, Z., Leon, L., Ramin-Mangata, S., Baty, T., Fall, F., Billon-Crossouard, S., Aguesse, A., Hollstein, T., Sullivan, D. R., Nobecourt, E., Lambert, G., and Krempf, M. (2017) Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD? Diabetes Metab

Croyal, M., Fall, F., Krempf, M., Thedrez, A., Ouguerram, K., Ferchaud-Roucher, V., Aguesse, A., Billon-Crossouard, S., Mata, P., Alonso, R., Lambert, G., and Nobecourt, E. (2017) Plasma PCSK9 measurement by liquid chromatography-Tandem mass spectrometry and comparison with conventional ELISA. J Chromatogr B Analyt Technol Biomed Life Sci 1044-1045, 24-29

Cournot, M., Lenclume, V., Le Moullec, N., Debussche, X., Doussiet, E., Fagot-Campagna, A., and Favier, F. (2017) Prevalence, treatment and control of hypertension in La Reunion: the REDIA population-based cohort study. Blood Press 26, 39-47

Chaudhari, N., Talwar, P., Lefebvre D’hellencourt, C., and Ravanan, P. (2017) CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells. Front Mol Neurosci 10, 310

Casemayou, A., Fournel, A., Bagattin, A., Schanstra, J., Belliere, J., Decramer, S., Marsal, D., Gillet, M., Chassaing, N., Huart, A., Pontoglio, M., Knauf, C., Bascands, J. L., Chauveau, D., and Faguer, S. (2017) Hepatocyte Nuclear Factor-1beta Controls Mitochondrial Respiration in Renal Tubular Cells. J Am Soc Nephrol 28, 3205-3217

Bohli, N., Chammem, H., Meilhac, O., Mora, L., and Abdelghani, A. (2017) Electrochemical Impedance Spectroscopy on Interdigitated Gold Microelectrodes for Glycosylated Human Serum Albumin Characterization. IEEE Trans Nanobioscience 16, 676-681

Baret, P., Le Sage, F., Planesse, C., Meilhac, O., Devin, A., Bourdon, E., and Rondeau, P. (2017) Glycated human albumin alters mitochondrial respiration in preadipocyte 3T3-L1 cells. Biofactors 43, 577-592


Tarnus E., Baraka Vidot J., Dorsemans A.C. and Bourdon E., What is the scale on my histological drawings? A blood tip at La Reunion island University Arch Med Biomed Res. 2016 in press

Septembre-Malaterre A., Stanislas G., Douraguia E. & Gonthier M-P. Evaluation of nutritional and antioxidant properties of the tropical fruits banana, litchi, mango, papaya, passion fruit and pineapple cultivated in Réunion French Island. Food Chemistry. 2016, in press

Parimisetty A, Dorsemans AC, Awada R, Ravanan P, Diotel N, Lefebvre d’Hellencourt C. Secret talk between adipose tissue and central nervous system via secreted factor ; an emerging frontier in the neurodegenerative research Journal of Neuroinflammation 2016 13(1):67. 

Septembre-Malaterre A, Le Sage F, Hatia S, Catan A, Janci L, Gonthier MP. Curcuma longa polyphenols improve insulin-mediated lipid accumulation and attenuate proinflammatory response of 3T3-L1 adipose cells during oxidative stress through regulation of key adipokines and antioxidant enzymes. Biofactors. 2016

Couret D, Boumaza D, Grisotto C, Triglia T, Pellegrini L, Ocquidant P, Bruder NJ, Velly LJ. Reliability of standard pupillometry practice in neurocritical care: an observational, double-blinded study. Crit Care. 2016 20(1):99.

E Frumence, M Roche,P Krejbich-Trotot, C El-Kalamouni, B Nativel, P Rondeau, D Missé, G Gadea, W Viranaicken, P Després. The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-ß production and apoptosis induction Virology 2016 493:217-226.

A Loregger, EC Cook, JK Nelson, M Moeton, LJ Sharpe, S Engberg, M Karimova, G Lambert, AJ Brown, and N Zelcer. A MARCH6 and U3 ubiquitin ligase circuit uncouples cholesterol synthesis from lipoprotein uptake in hepatocytes Moll Cell. Biol. 2016 36, 285-294.

G Lambert, N. Diotel, and H Tavori  The biology of PCSK9 inhibition: some unanswered questions Eur. Heart Journal. 2016 in press.

Diotel N, Vaillant C, Kah O, Pellegrini E. Mapping of brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation Gene Expr Patterns. 2016 20(1):42-54.

Guilleminault L, Houksel H, Leguic C, Leguen Y, GermaudP, Desfleurs E, Leroyer C, Magnan A. A new concept in asthma: from personalised curative medicine to personalised preventive medicine. Eur Resp Rev. 2016; In press

A Thedrez, B Sjouke, M Passard, S Prampart-Fauvet, A Guédon, M Croyal, G Dallinga-Thie, J Peter, D Blom, M Ciccarese, A Cefalu, L Pisciotta, RD Santos, M Averna, F Raal, P Pintus, M Cossu, K Hovingh, and G Lambert . PCSK9 inhibition for Autosomal Dominant Hypercholesterolemia Thromb. Vasc. Biol. 2016 in press.

Boyer, F., Diotel, N., Girard, D., Essop, M.F., Rondeau, P. and Bourdon, E.  Enhanced oxidative stress in adipose tissue from diabetic mice, possible contribution of glycated albumin Biochem Biophys Res Commun. 2016 in press.

Fessard, A., Bourdon, E., Payet, B. and Remize, F. Identification, stress tolerance and antioxidant activity of lactic acid bacteria isolated from tropically-grown fruits and leaves Can J Microbiol. 2016 in press.

Somanah, J., Ramsaha, S., Verma, S., Kumar, A., Bharty, R.K., Chaudhary, A.K., Sharma, P., Aruoma, O.I., Bourdon, E. and Bahorun, E. Fermented papaya preparation modulates the progression of N-methyl-N-nitrosourea induced hepatocellular carcinoma in balb/c mice Life Sci. 2016 in press.

Delbosc S, Rouer M, Alsac JM, Louedec L, Philippe M, Meilhac O, Whatling C, Michel JB: Elastase inhibitor AZD9668 treatment prevented progression of experimental abdominal aortic aneurysms. J Vasc Surg 2016, 63(2):486-492 e481.


Alves AC, Etxebarria A, Medeiros AM, Benito-Vicente A, Thedrez A, Passard M, Croyal M, Martin C, Lambert G, Bourbon M. Characterization of the First PCSK9 Gain of Function Homozygote. J Am Coll Cardiol. 2015 66(19):2152-4.

Chammem H, Hafaid I, Bohli N, Garcia A, Meilhac O, Abdelghani A, Mora L. A disposable electrochemical sensor based on protein G for High-Density Lipoprotein (HDL) detection. Talanta. 2015 144:466-73.

Hyafil F, Tran-Dinh A, Burg S, Leygnac S, Louedec L, Milliner M, Ben Azzouna R, Reshef A, Ben Ami M, Meilhac O, Le Guludec D. Detection of Apoptotic Cells in a Rabbit Model with Atherosclerosis-Like Lesions Using the Positron Emission Tomography Radiotracer [18F]ML-10. Mol Imaging. 2015 14:433-42.

Septembre-Malaterre A., Hatia S., Lallemand L., Césari M., Douraguia E., Libelle T.  Gonthier M-P. Characterization of French Victoria pineapple antioxidant micronutrients and polyphenol protective effect on preadipose cells exposed to oxidative stress. International Journal of Food and Nutritional Sciences. 2015, 4(5): 1-11.

Blirando K, Blaise R, Gorodnaya N, Rouxel C, Meilhac O, Vincent P, Limon I. The stellate vascular smooth muscle cell phenotype is induced by IL-1β via the secretion of PGE2 and subsequent cAMP-dependent protein kinase A activation. Biochim Biophys Acta. 2015 1853(12):3235-47.

Rubio-Navarro A, Amaro Villalobos JM, Lindholt JS, Buendía I, Egido J, Blanco-Colio LM, Samaniego R, Meilhac O, Michel JB, Martín-Ventura JL, Moreno JA. Hemoglobin induces monocyte recruitment and CD163-macrophage polarization in abdominal aortic aneurysm. Int J Cardiol. 2015 201:66-78.

Besnier F, Lenclume V, Gérardin P, Fianu A, Martinez J, Naty N, Porcherat S, Boussaid K, Schneebeli S, Jarlet E, Hatia S, Dalleau G, Verkindt C, Brun JF, Gonthier MP, Favier F. Individualized Exercise Training at Maximal Fat Oxidation Combined with Fruit and Vegetable-Rich Diet in Overweight or Obese Women: The LIPOXmax-Réunion Randomized Controlled Trial. PLoS One. 2015 10(11):e0139246.

Cheng JM, Akkerhuis M, Malaud E, Piquer D, Merle D, Meilhac O, van Geuns RJ, Boersma E, Kardys I, Fareh J Evaluation of 42 cytokines, chemokines and growth factors for prediction of cardiovascular outcome in patients with coronary artery disease. Int J Cardiol. 2015 184:724-7

Blache, D., Bourdon, E., Salloignon, P., Lucchi, G., Ducoroy, P., Petit, J.M., Verges, B . and Lagrost, L. Glycated albumin with loss of fatty acid binding capacity contributes to enhanced arachidonate oxygenation and platelet hyperactivity: relevance in patients with type 2 diabetes  Diabetes 2015 64, 960-972

Baraka-Vidot J., Planesse C., Meilhac O., Militello V., Van den Elsen J., Bourdon E. and Rondeau P., Glycation alters ligand-binding, enzymatic and pharmacological properties of Human albumin Biochemistry 2015 54, 3051-62Pubmed

Boyer F., Baraka Vidot J., Guerin Dubourg A., Rondeau P., Essop F., Bourdon E. Oxidative Stress and Adipocyte Biology – Focus on the Role of AGEs. Oxid Med Cell Longev 2015 2015:534873.Pubmedpdf

Planesse C, Nativel B, Iwema T, Gasque P, Robert-Da Silva C, Viranaïcken W. Recombinant human HSP60 produced in ClearColi™ BL21(DE3) does not activate the NF-kB pathway Cytokine. 2015 73 :190–195.-pdf

Viales RR, Diotel N, Ferg M, Armant O, Eich J, Alunni A, März M, Bally-Cuif L, Rastegar S, Strähle U. The helix-loop-helix protein id1 controls stem cell proliferation during regenerative neurogenesis in the adult zebrafish telencephalon Stem Cells. 2015 33(3):892-903Pubmed

Baraka-Vidot J, Denemont I, Ali MColo Z, Bourdon E, Rondeau P. Ammonium Sulfate Precipitation but Not Delipidation is a Valuable Method for Human Albumin Preparation for Biological Studies. J Dia Clin Diag 2015 2:109 –pdf

Coumailleau P, Pellegrini E, Adrio F, Diotel N, Cano-Nicolau J, Nasri A, Vaillant C, Kah O.Aromatase, estrogen receptors and brain development in fish and amphibians. Biochim Biophys Acta. 2015 Feb;1849(2):152-162. Pubmed

Marimoutou M, Le Sage F, Smadja J, Lefebvre d’Hellencourt C, Gonthier MP, Robert-Da Silva C. Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H2O2, TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes. J Inflamm (Lond). 2015 12:10Pubmedpdf

O. Najam, G. Lambert, and K.K. Ray The past, present and future of lipid lowering therapy Clin Lipidol 2015 10, 481-498.ARCHIVES 2011 2014